My doctor assigned me Cymbalta to help with the pain in my joints and back,. After taking one pill I woke up the next day with horrible swelling in my hands and feet and twice as much pain as before. I tried the pills a couple more times over the following month, always with the same effects. When I told my doctor about my symptoms she said the immediate increase in pain and intense swelling meant the drug was working. I'm very confused to say the least, I thought the drug is supposed to help the pain, not double it., .