I Just Heard a Drug (Pfizer) Advertised, Lyrica, for Fibromyalgia, has Anyone Out There Have Experience With-?
-this Drug?
From their Website:
LYRICA is the first and only FDA-approved treatment that can help relieve fibromyalgia pain.
Fibromyalgia is one of the most common chronic widespread types of pain in the U.S. It can make daily activities difficult.
Thanks amielou, but Looks to me Like Another Big Parm. Company Cashing In On a Condition, I Suspect it is Not Inexpensive.
Thanks Dani C, but I'm Not Considering Using it for Myself.
Thanks Medicine Woman and DNA G, Consistent With my Very Little Reading About the Drug, 6 Weeks?, Sounds Like a Antidepressant.
Thanks K, I Looked At Lyrica More Closely, it Acts Though a G-Protein Coupled Receptor (Like Antihistamines), So, I Suspect Whatever Action it has, it isn't Forever, Like Antihistamines.
m r, Like CFS? "Depression"?
Some Might Find this Interesting (From Wikipedia):
Receptor regulation
GPCRs become desensitized when exposed to their ligand for a prolongued period of time. There are two recognized forms of desensitization: 1) homologous desensitization, in which the activated GPCR is downregulated and 2) heterologous desensitization, where the activated GPCR causes downregulation of a different GPCR. The key reaction of this downregulation is the phosphorylation of the intracellular (or cytoplasmic) receptor domain by protein kinases.
[I Suspect Another Regulation is Going On: Receptor Expression, One Can Envision to Scenarios for this: Agonism. Atagonism, A Cell Making Fewer Receptors for Ligand or More.]
I'm Sorry, Two Scenarios.
Public Comments
1. a guy that I use to work with took it and he said that it worked great. on the other hand my father took it and said it did not work. however my father is also a drug seeker. try it2. I demolished my right leg in a car accident in July. I have some nerve damage due to the car crash. No nerves were severed, but they are damaged leading to pain and paralysis. I was prescribed lyrica, along with a couple narcotic pain relievers. The lyrica was specifically for my nerve pain though. I did not find relief with it, and it did have side affects on my vision. I am now taking cymbalta for my nerve pain, but others consider lyrica a miracle drug. If you try it, you need to give it a chance. At least a month to see true results. Good luck!
3. My neurologist gave it to me for Eagle's Syndrome and Fibromyalgia and it did not work at all. It was like eating candy to see if the pain would stop. Once I took more than prescribed and it made me dizzy but the pain was still there. I would not recommend it to anyone who suffers from pain. It might work if the pain is very mild but why take a prescription for mild pain when you can take Tylenol. As a matter of fact, Advil worked better for me than Lyrica.
4. It is used for neuropathic pain. But, you don't take it like Tylenol or a narcotic. You need to build up levels in your blood stream and you won't see any results for several weeks. It's expensive and most insurance companies will not cover it because it is very similar to gabapentin which is generic and cheap.
5. I can just tell you that the serious neurologists I have worked with at the hospital think it is completely useless, and just another laboratory strategy to make more money.
But also... I don't really think fibromyalgia exists either... I just think it's a pretty label to put on people who are lazy or get tired too easily.
