lyrica for fibromyalgia drug treatment Knowledge Base
I Just Heard a Drug (Pfizer) Advertised, Lyrica, for Fibromyalgia, has Anyone Out There Have Experience With-? -this Drug? From their Website: LYRICA is the first and only FDA-approved treatment that can help relieve fibromyalgia pain. Fibromyalgia is one of the most common chronic widespread types of pain in the U.S. It can make daily activities difficult. Thanks amielou, but Looks to me Like Another Big Parm. Company Cashing In On a Condition, I Suspect it is Not Inexpensive. Thanks Dani C, but I'm Not Considering Using it for Myself. Thanks Medicine Woman and DNA G, Consistent With my Very Little Reading About the Drug, 6 Weeks?, Sounds Like a Antidepressant. Thanks K, I Looked At Lyrica More Closely, it Acts Though a G-Protein Coupled Receptor (Like Antihistamines), So, I Suspect Whatever Action it has, it isn't Forever, Like Antihistamines. m r, Like CFS? "Depression"? Some Might Find this Interesting (From Wikipedia): Receptor regulation GPCRs become desensitized when exposed to their ligand for a prolongued period of time. There are two recognized forms of desensitization: 1) homologous desensitization, in which the activated GPCR is downregulated and 2) heterologous desensitization, where the activated GPCR causes downregulation of a different GPCR. The key reaction of this downregulation is the phosphorylation of the intracellular (or cytoplasmic) receptor domain by protein kinases. [I Suspect Another Regulation is Going On: Receptor Expression, One Can Envision to Scenarios for this: Agonism. Atagonism, A Cell Making Fewer Receptors for Ligand or More.] I'm Sorry, Two Scenarios.
Vegetarian and prescription drugs??? Are there any vegetarian treatments for fibromyalgia? So, I am a vegetarian, have been a long time, (and am recently trying to transition into becoming a vegan). So, my rheumatologist presrcibes me lyrica, to treat fibromyalgia. In the meantime, they are doing bloodwork to check for autoimmune problems....anyway, I tell them that the lyrica, is not vegetarian (gelatin). And she says some of my other meds aren't either. The only other I take is topamax (for migraines) which she says has stearic acid, which isn't vegetarian either. Which I looked up and will have to stop taking this, stearic acid, that is. So, she says that the meds for fibromyalgia are not going to be vegetarian, and my alternative is pilates, yoga, etc. Which I do, but not very often. Are there NO vegetarian or vegan treatments for fibromyalgia, or headaches/migraines?? Really?
Doctors not treating fibromyalgia? Dear doctor, When a fibromyalgia patient comes to you and they are in tears because they live day in and day out in terrible pain it is not right ofyou to assume they are depressed and send them on their way with antidepressants telling them it is their depression causing their pain. It is you dear doctor that is causing their depression. How? Well when people are in pain they beleive the doctor will do everything they can to ease their suffering and when the doctor fails to treat their pain or take it seriously the patient is sent out the door with no hope. What are the patients options? Well they can go to the ER on a regular basis and be emotionally abused some more by the staff and then marked as a drug abuser or at the least made to feel that way. Or they could just go home and commit suicide. I have read several stories on people with Fibromyalgia who have commited suicide and if you would like to hear one of them just go to youtube and look up Fibromyalgia and suicide. People with Fibromyalgia are very lucky when they find a caring doctor but they are few and far between. Doctor if you had to live one ay in the life of a person with Fibromyalgia I garauntee that your approach on this matter would change greatly. You would become obsessed with finding a cure and in the meantime bring as much releife to those suffering from Fibromyalgia as possible. It is not fun to wake up with a head ache, stiff back, sore legs, sore stiff kneck, and pain shooting through out every joint, muscle and bone of your body. To top it off your tired because the sleep you did have was not refreshing enough or you could only sleep a couple of hours because the pain didn't let up. I ask you does this sound pleasant? Does it sound like something that you should just learn to live with. I ask you what would it feel like to break your leg and dislocate a shoulder and go to work and act as though everything is fine. Wouldn't the pain be to much? Well for allot of people with Fibromyalgia the pain is to much and when the patients cry the doctors are not moved in any way to find their patient, the one they are suppose to be CARING for a good treatment plan to treat their pain. Some doctors say oh Lyrica it's the Fibromyalgia miracle drug. I can tell you doctor that it is not the case at all. It might help some people, but it doesn't help as many as you all would like us to beleive. Frankly for most it causes more problems than it's worth. This whol exercise and loose weight thing is for the birds too! Can you beleive that allot of people suffering from fibromyalgia were thin or at least at a healthy weight before they were left to suffer. People with fibromyalgia are not looking for an easy way out as some nurses and doctors beleive. I know I have read through doctors and nurses blogs. I see what they think of people sufferinf from fibromyalgia. They think we want disability and that we want to be on drugs. Well I can tell you doctor that my doctors office doesn't write out narcotic pain medciation and if that was what I was after I could have easily change to a doctor I know that will. Also if I was afterdisability I would already have applied since I have not been able to work in more than a year. I keep hoping that I will find the help I need so that I can go back to work and resume as much of anormal life as possible. I have played the guinea pig for far to long and have been made very sick several times in the process. I'm tired of this. I know what works for me, but dare I ask and have you think I'm a drug abuser. I know what works for me because times when I have had UTI pain and been given pain medication for it. I used those pain meds to treat my Fibromyalgia pain and guess what doctor I felt good for the short time I had them. As in good I mean normal, I could clean my own home, sleep at night, and if that was my regular medication I could have possibly even went back to work. I'll keep quite though for fear if I mention one thing particular that I know will help you will automaically assume I'm addicted to this particular drug and my pain would never stand a chance of beinf treated or taken seriously. So for now I'm your little guinea pig doctor. How long will it take you to realise that all you have to do is give me pain medicine and I could be able to function. Drug test me I don't care, but you might be surprised to learn I have no drugs in my system and also you might be surprised if you do a back ground check and see that I have never had a drug problem! sincerely your guinea pig, A fibromyalgia sufferer
What test should a Doctor run to rule out fibromyalgia? I am 22 years old and have been suffering from chronic muscle, joint, and tendon pain since February of 2005. My symptoms are as follows: --shooting pain from my elbows to my figures ( feels like funny bone constantly being rubbed) --tight muscles in my back and neck, puts painful pressure on my spine . --muscles around along my spine are like tough strings, you can actually pluck, and make cracking sounds --sever pain in my wrist and finger joints that causes inconvenience and limitations. can not turn door knobs, open bottles, write long periods of time, drive etc. --wake up frequently through out the night --feel sore and stiff in the mronings, as if just completed an intense work out, or hadn't slept for weeks and can't keep my balance. --Have to rely on high amounts of caffeine to get me through the morning and to get me through my daily schedule of work and school. --extreme exhaustion, even after full nights of sleep. I have fallen asleep while driving on several occasions. I am currently diagnosed with fibromyalgia and am on: 150mg of Lyrica, 50mg of Ultram/Tramodol, and 800mg of ibuprophene 3 times a day; as well as 150 - 200mg of Trazodone at night for sleep and depression. These medications started of much lower and have increased as my systoms have. I have also tried cymbalta, vicodine, ambian, Urtram CR, Soma, Flexeril, and Topamax; along with massage and physical therapy, trigger point injections and chiropractors. Unlike most cases, I was diagnosed with fibromyalgia fairly quickly. Only after about a year of seeing doctor after doctor. I've had blood test, MRIs of my back, and x-rays of my back and hands. Although they have found deterioration of my bones in my hands, and 3 discs in my spine, I been told this shouldn't be causing this type of pain. All the other test listed came back normal. I feel as if they are disregarding me due to my age, and that the fibromyagia diagnoses was a quick fix. My questions is, I have heard fibromyagia should only be diagnosed if EVERYTHING else has been ruled out. What other test should my Doctors be running to ensure this isn't something else. I have done some research and found these following names, but my little country Doctors out here in NC said they haven't heard of them. Does anyone have any feed back on these: Arthrography Discogram Epidurography Facet Nerve and Joint Injection MRI Arthrography Myelogram I would also like to add I overdosed on cocaine and alcohol in August of 2004, 6 months prior to these sysmtoms. It was a mistake I made while hanging out with the wrong crowd, and trying to look tough. Have seeked help for this, and do not drink, or do drugs and am very careful about using my medications only as prescribed. I am alway reluctant to tell my Doctors this in fear that they will think I a pill seeker. Could this be useful information for them, or harmful to my treatment? Could this be connected to the cause of these symptoms?
Whatt kinds of reactions do people get after the H1N1 flu vaccination? Since it is not covered by the regular flu shot, it is still pretty much a brand new big pharmaceutical industry field. Big pharma seems to be getting as lot of negative publicity lately eg. *************************************************************************** The Pharmaceutical Industrial Complex: A Deadly Fairy Tale By Dr. Doug Henderson and Dr. Gary Null URL of this article: www.globalresearch.ca/index.php?context=va&aid=15758 Global Research, October 21, 2009 Progressive Radio Network - 2009-10-20 It has been a particularly bad month for the pharmaceutical industrial complex in its ongoing litigations in American courts. Among the main pharmaceutical headlines, Merck s Gardasil vaccine for HPV, now being widely administered to pre-teens, was found to be linked to amyltrophic lateral sclerosis, commonly known as Lou Gehrig s disease; following a $1.4 billion fine in promoting one of its blockbuster drugs Zyprexa off-label, deceptive correspondence was uncovered by Eli Lilly gaming the system again by promoting another one of its drugs, Cymbalta, off-label for fibromyalgia; AstraZeneca was fined $160 million for scamming the Medicaid system in Kentucky after being fined $215 million for ripping off Alabama; Glaxo lost a Pennsylvania trial for failing to warn doctors and pregnant women of the dangers of its antidepressant drug Paxil related to birth defects; and Pfizer scored a record-breaking fine of $2.3 billion for illegally marketing several drugs over the years: Bextra, Zyvox, Geodon and Lyrica. These kinds of charges, among the many others, have become a habit for drug makers for the past dozen years. When we speak of the pharmaceutical industry complex, it does not refer solely to private drug manufacturers. The complex, like a Matrix that holds captive the health of the nation in medical slavery by its own design and manipulation, is a consortium, a spiders web woven with financial attachments throughout the medical profession. In addition to the pharmaceutical and medical device firms, this complex includes every government health agency the Food and Drug Administration (FDA), the Centers for Disease Control (CDC), the National Institutes of Health (NIH), and or course the Department of Health and Human Services (HHS) as well as drug lobbying firms now employing a large number of former Congresspersons, insurance and HMO companies, all of the leading professional medical associations such as the American Medical Association (AMA) and the American Psychiatric Association (APA), the majority of medical schools and their research departments who are heavily funded by drug money, many of the most prestigious medical journals, and ultimately all of this filtering downward to the physicians who diagnose our illnesses and prescribe our medications and treatments. America is rightly regarded as having led much of the world in many qualitative innovations in all fields. That reputation is duly deserved. However, there is a new dynamic at work that is causing this reputation to be challenged. We are a nation that prides itself in our humanity, our sense of fairness, but today there is a growing concern that we are now being monikered as a country held hostage to a national security complex, which includes the largest military complex in the world, an obscenely expensive healthcare system and self-serving bureaucracies and private industries that serve their own financial ends. So it is not surprising that after spending this year $2.6 trillion on healthcare, we have such little health to show for it. There are second world countries where people live longer and healthier lives. And we have the worst healthcare among developed nations. So what have we received for our $2.6 trillion. As the current healthcare debate continues to rage over in sundries the $200 billion net profit health insurance industry the entire deliberation over disease prevention and treatment has been overshadowed. And amidst this partisan and ideological anarchy, perpetuated by our elected officials, the media, and fueled by the pharmaceutical complex, two other areas America excels as a leader above all other developed nations is in being the premier breeding ground for the pharmaceutical industrial complex s greatest profits and, second, as the world s exemplar in medical fraud and corruption. The fairy tale of America s health as being best served by drugs is a creation of this complex, a lullaby that brings ill citizens repeatedly to their doctors and hospitals for diagnosis and treatment, or simply to deny healthcare altogether to the uninsured. The country is pacified by a blind belief that the drugs being prescribed to them have been proven safe because our government health agencies have our physical health and well-being in their best intentions. This is a lie, an extraordinarily deadly lie. Iatrogenesis, medically induced injury and death, is the number one cause of death in Am
who are tehse cyber police i have been reported to? HERES THE SITUATION this question was posted: I DID NOT ADDRESS HER IN AN ABUSIVE MANNER AT ALL--i have told people off who have attcked me first...I have always politely relayed my knowledge of fibro---from my extensive research into traditional and alternative methods... so heres teh quetsion--who are these cyber police she refers to? i woudl like them to contact me What is the best Medicine for Fibromyalgia? Which is the best medicine for Fibromyalgia besides Lyrica I cannot take any NSAID'S Like Motrin or Naproxen because of GastroEsophageal Reflux Disease? There were 2 repsonses: the first from AL (not her real name) Omega 3 Oils and Magnesium. Get it from your diet as well. Stop eating processed foods. Stop eating fried foods. Stop eating wheat. Find an alternative source for calcium - stop consuming dairy products. MY RESPONSE: there is no best medicien--it is differnt fr every one NSAIDS don't work as tehri is no inflammtion the otehr 2 approved meds are CYMBALTA and SAVELLA whicha re SNRIs--also other neds that regulate teh neuro transmitters you cna try alternatives to LYRICA--other anti seizure meds--not helped me... rela fms is a neuro condition--any treatment--even alternative neneds to focus of regulating teh neuro suystem be carefula bout what people say cured tehm--fms is highly over diagnosed by incompetant docs--many are stiulll saying ther is inflammtion---people taht have been cured never had real fms NOTICE TEHRE ARE ONLY 2 RESPONSES each 1 has ONE thumbsdown THIS IS THE SCATHING EMAIL I GET FROM AL (she does not allow email from me) From: AL Subject: You need to get a medical background job... Message: ...so that you can get registered to receive real medical information both in lectures and snail mail and on the Internet by paying for it. One medical researcher doing "research" on YOU does not constitute peer reviewed medical knowledge. Read "The Inflammation Cure " by toxicology and immunology professor William Joel Meggs. "Fibromyalgia" involves inflammation unseen by the naked eye. It is in the brain. Get yourself a reputable neurologist - a movement disorder one. Have a gentetic screening test done and start making yourself healthy with food instead of advising the misinformed to take more drugs with many side-effects. Stay out of the sun. Any good medical doctor knows that there are foods that promote inflammation and foods that reduce inflammation. However unscrupulous ones enjoy using uninformed ones as guinea pigs to try out new medicines and bogus, not peer reviewed treatments. Diet does work. I am living proof. I have a progressive neurological condition as well as a medical background. Stop hacking into peoples accounts and using multiple YA accounts to annoy people. I have reported you to the appropriate police unit for cyber crime in the past. They know who you are. ********************************************************************************** here are teh real faxcts: FIBROMyalgia is accepted to be a neurologicAL CONDITION With NO INFLAMMTION--this theory is uphelp by teh top researchers around teh world It is true taht diet willhelp optimize teh body and make it stronger to deal with teh Fibromylagia--and possibly help reduce teh symptoms but it will not control fibro like AL claims... there are many conditions that mimic fibro--and at least one of tehm will be comtrol with diet alone i ahve particiapted in legitimate researc=h with world renowned resaerchers taht are published and peer reviewd and her sattement about tehr beign invisable inflammtion is how shoudl i say it---in appropriate so i could refute everything she said--with ACCPETED RESEARCH i ahve never claiemnd to eb a medical professional (she has) STOP HACKING INTO ACCOUNTS ( iw oudln't if i copudl) STOP USING MULTIPLE ACCOUNTS (ther eis one otehr answer here--and one thumbs down--how does taht indicate i am using mulitple acounts--yes i ahve an old account--but only 1 i am currently using..i got a new email address due to sapm so i had to start a new account) i have tried a fibro friendly diet--and got worse--so I am living proof taht diet doesn't cure fibro the quetsion is who are these cyber police --i woul dlove to talk to tehm sorry for teh typing--due to my diability btw--filing a false police report is a crime in teh real world i am in teh US--i don't knwo where she is jem--i wish you were --so i coudl report her to you.. her wild accusations just further prove that she is unstable and her information is just as crazy as she is
Fibromyalgia pain medication? i have a dr appt may 10. i had to go to the er cause the pain got so bad. the er dr asked what i was doing for my break through pain??? i didnt know how to respond. my dr has only given me vicodin 7.5 for PAIN. the vicodin only works on my regular pain, but when it gets really bad it doesnt touch it, is that what he means? anyway he also asked if i had tried pain patches, i have never heard of these. he suggested i make an appt with my reg dr and ask these questions. 1. am i being treated for chronic fatigue syndrome- he believes i have this and it is related to my fibro 2. getting something for breakthrough pain or being put on a pain patch. 3. what is my fibro treatment plan do these sound like normal questions to ask my doctor? i dont want her to think i am just wanting more drugs, but i have been on the same pain meds for 3 years and they are not working. so i guess my quesiton is, how do i go about asking these questions without looking like a junkie, drug seeker? also, for those with fibro, are you on any pain patches, higher pain meds like the er dr mentioned to me? he mentioned that for paients like me where cymbalta, lyrica and other meds didnt work pain meds are really the only other then to help with "quality of life". please give me your experiences. I already get nervous every appointment that she will not want to continue my viccodin, and now he wants me to ask for something new..... not sure what to do, and very nervous to say a pain pill is not working, i mean i think she will think i am a crazy druggy